Dementia can be caused by hypertension?
Dementia can be caused by hypertension?
Hypertension is a chronic condition that causes dynamic organ damage. It
is shown that most by majority of cases of Alzheimer's disease and related
dementia are not because of genetic predisposition but rather to chronic
exposure to vascular risk factors.
The clinical approach to treatment of dementia
patients for the most part begins simply after side effects are clearly
evident. However, it has turning out to be progressively certain that when
indications of brain damage are manifest, it might be past the point where it
is possible to switch the neurodegenerative process. hypertension despite
everything need methods for evaluating movement markers that could exposed
pre-symptomatic alterations and identify patients in danger of developing
dementia. The work was conducted on patients with no effects of structural damage
and no diagnosis of dementia. All
patients Stand clinical examination to determine their high blood pressure
status and the related target organ risk. Additionally, patients were interested
to an MRI scan to know microstructural damage. To improve insights in the
neurocognitive profile of patients a specific group tests was conducted. Researchers
target is major outcome of the study at finding any specific mark of brain
changes in white matter microstructure of hypertensive patients, associated
with an impairment of the related cognitive functions.
The result indicated that hypertensive patients prove important
alterations in three specific white matter fiber-tracts. patients of hypertensive also mainly worse in the
cognitive domains ascribable to brain regions interlinked through those
fiber-tracts, presenting decreased performances in executive functions,
processing speed, memory and related learning tasks. Overall, white matter
fiber-tracking on MRIs indicate an early sign of risk in hypertensive patients
when otherwise undetectable by conventional neuroimaging. As these changes by absorbing
before patients have symptoms, these patients could be targeted with medication
earlier to prevent further deterioration in brain function. These findings are
also rarely applicable to other forms of neurovascular illness,
where early intervention could be of marked therapeutic benefit.
"The problem is that neurological alterations related to high blood
pressure are usually diagnosed only when the cognitive deficit becomes proved,
or when traditional magnetic resonance shows clear indication of brain damage.
In both cases, it is often too delay to stop the pathological process.
We have been able to observe that, in the hypertensive cases, there was identification
of white matter fibers connecting brain areas typically include in attention, feelings
and memory. It is an important issue to consider is that all the hypertensive
patients studied did not show clinical mark of dementia and, in conventional
neuroimaging, they showed no signs of cerebral damage. However, further studies
will be important, but we thought that the use of tractography will lead to the
early identification of people at risk of dementia, allowing timely therapeutic
interventions."
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